Mouse HMGCR ELISA Kit: Essential for Cholesterol & Metabolic Research
Yanda Bio’s Mouse 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase (HMGCR) ELISA Kit is a sensitive and specific assay designed for the quantitative measurement of HMGCR activity or protein levels in mouse liver tissue homogenates, cell lysates, and other relevant samples. As the rate-limiting enzyme in the mevalonate pathway, HMGCR is the primary target of statin drugs and a central research focus in studies of cholesterol metabolism, cardiovascular disease, and lipid biology.
As a factory-direct manufacturer, we offer premium ELISA kit production at transparent, competitive prices. This kit serves as a reliable and cost-effective ELISA kit alternative to major suppliers, delivering robust performance optimized for mouse models. Optimize your research budget without compromising on data quality or reliability.
Choose Your Optimal Assay Format: Balance Performance & Value
To cater to different research needs and budgets, we offer two meticulously optimized formats for the Mouse HMGCR ELISA Kit. Purchasing either tier includes our complimentary expert sample testing service.
| Feature | Tier 1: Standard HMGCR ELISA Kit | Tier 2: High-Sensitivity HMGCR ELISA Kit |
|---|---|---|
| Core Technology | Optimized one-step sandwich ELISA with a proprietary background-suppression diluent. | Biotinylated recombinant monoclonal antibody (>95% pure) + Streptavidin-HRP conjugate (≥500 U/mg). |
| Key Advantage | Exceptional Value & Proven Reliability (>99% success rate). Uses a simultaneous incubation step. The specialized diluent minimizes background from hemoglobin and lipids, ensuring robust, consistent performance. | Maximum Sensitivity & Matrix Resistance. The advanced biotin-streptavidin system directly overcomes matrix effects, providing unparalleled signal-to-noise for the most demanding samples or low-abundance targets. |
| Our Selection Advice | Ideal for routine cholesterol/metabolism studies. Choose this tier for outstanding value, with a retail price of $120 and bulk pricing under $100. | Recommended for precious/rare samples or detecting subtle regulatory changes. Invest in this tier to ensure first-attempt success in critical experiments. |
| Best For | High-throughput screening, standard research on lipid metabolism, and budget-conscious projects. | Studies with limited sample volume, low-expression models, or requiring the highest precision. |
Complimentary Expert Testing Service
Validate your assay or save valuable lab time with our professional service, included with every kit purchase.
- Fast Turnaround: We begin analysis within 24 hours of sample receipt; deliver a full report in ~5 business days.
- Complete Data Package: Receive raw OD values, calculated concentration/activity tables, and a standard curve graph.
Why Choose Yanda Bio’s HMGCR ELISA Kit?
- Direct Manufacturer Price: Source Mouse HMGCR ELISA Kit with manufacturer price directly, eliminating distributor markups.
- Custom & Production Flexibility: We offer ELISA kit custom service and reliable in-house ELISA kit production for specialized requirements.
- Publication Reward: Cite this kit with a link to our site in your publication, and receive a free standard ELISA kit.
- 100% Satisfaction Guarantee: We promise performance with an unconditional replacement or refund policy.
- 24-Hour Support: Get a proposed solution within one business day.
Assay Principle & Specifications
Detection Principle: This sandwich ELISA captures mouse HMGCR between an immobilized antibody and an HRP-conjugated detection antibody. TMB substrate reaction, measured at 450 nm, yields a signal proportional to HMGCR levels.
Performance Specifications:
- Sensitivity: < 1.0 U/L.
- Detection Range: 1.0 – 80 U/L.
- Accuracy: R ≥ 0.9900.
- Precision: Intra- & Inter-assay CV < 15%.
- Specificity: High specificity with minimal cross-reactivity.
- Storage: 2-8°C; 6-month shelf life.
Sample Preparation: For liver or other tissues, use appropriate homogenization buffers. For cells, prepare lysates accordingly. Centrifuge serum/plasma at 3000×g for 10-30 mins. Aliquot and store at -20°C, avoiding freeze-thaw cycles. A 1:5 dilution is typically required for liquid samples.
Ordering, Custom Services & Support
| Option | Description | Details |
|---|---|---|
| Tier 1: Standard Kit | Cost-effective solution for common research applications. | Retail: $120. Bulk: <$100 (quote required). |
| Tier 2: High-Sensitivity Kit | Premium performance for critical, high-sensitivity applications. | Contact for manufacturer price. |
| Expert Testing Service | We run the assay and provide the full report. | Free with kit purchase. |
| Custom ELISA Development | Tailored Mouse HMGCR ELISA Kit customed to your specifications. | Project-based quote. |
Ready to buy a reliable, cost-effective Mouse HMGCR ELISA Kit? Contact Yanda Bio today for pricing or to discuss custom options.
Research Applications & FAQ
Primary Applications (RUO): Cholesterol biosynthesis research, statin drug mechanism studies, cardiovascular disease models (atherosclerosis), fatty liver disease (NAFLD), and general lipid metabolism investigations.
Q: Does this kit measure HMGCR protein concentration or enzymatic activity?
A: This ELISA kit is designed to measure levels related to HMGCR activity (U/L), providing a functional assessment crucial for metabolic studies, as indicated in the performance specifications.
Q: How does this kit compare to those from suppliers like Abcam?
A: Our Mouse HMGCR ELISA Kit offers comparable or superior sensitivity and specificity as a cost-effective elisa kits alternative, with added benefits: direct manufacturer support, bulk pricing under $100, and a complimentary testing service.
Q: Can this kit be used for samples from other species?
A: It is validated for mouse samples. For other species (e.g., rat), cross-reactivity is not guaranteed. Please inquire about our custom service for species-specific validation or development.
Q: How do I claim the free kit for publication?
A: Upon publication, send us the citation (DOI) of your article that cites “Mouse HMGCR ELISA Kit (Yanda Bio)” and includes a link to this product page.
Manufacturer’s Note
This product is for Research Use Only (RUO). It is not intended for diagnostic, therapeutic, or clinical procedures.
